Enabling Novel Insights in Drug Discovery

Bring your favorite assay into the cell!

Today
Biochemical screening does not capture the complexity of the intracellular space
With Portal
Cytosolic delivery of candidate molecules enables novel insights regardless of permeability
DELs in Cells: Portal has demonstrated robust delivery of DNA encoded libraries

Probing the intracellular space

Today
Most molecular probes, such as antibodies, are cell impermeable - restricting their utility
With Portal
Portal enables delivery of diverse probe molecules into cells for intracellular insights
Probes with Portal: Protein detection probes can be used to measure protein levels and their degradation in live cells