Light and dark purple banner with the title "Boba & Biotech with Armon Sharei" on top left and a cell cartoon holding a pitchfork on its left hand and pitch fork on the right hand. On the right side of the banner is a black and white picture of the host: Armon Sharei smiling.Light and dark purple banner with the title "Boba & Biotech with Armon Sharei" on top left and a cell cartoon holding a pitchfork on its left hand and pitch fork on the right hand. On the right side of the banner is a black and white picture of the host: Armon Sharei smiling.

Boba & Biotech is a candid podcast hosted by Portal Bio founder Armon Sharei, exploring the real challenges of drug development through conversations with scientists, entrepreneurs, and investors who are working to improve human health. Drawing from his own journey of raising $400M, going public, getting ousted from his first company, and starting over, Armon brings firsthand insight into the science, money, and corporate politics that shape the biotech industry.

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Most Recent Episode

Light and dark purple banner with the title "Boba & Biotech with Armon Sharei" on top left and a cell cartoon holding a pitchfork on its left hand and pitch fork on the right hand. On the right side of the banner is a black and white picture of the host: Armon Sharei smiling.
SEASON 106/18/2026

Building Precision NanoSystems and the Road to a Danaher Exit

In this episode of Boba & Biotech, Armon sits down with James Taylor, co-founder of Precision NanoSystems, for a candid conversation about building a manufacturing technology for nanoparticle-delivered RNA medicines from a PhD project into an 11-year journey that ended in an acquisition by Danaher Corporation, a leading global life sciences and diagnostics healthcare company. 

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Light and dark purple banner with the title "Boba & Biotech with Armon Sharei" on top left and a cell cartoon holding a pitchfork on its left hand and pitch fork on the right hand. On the right side of the banner is a black and white picture of the host: Armon Sharei smiling.
SEASON 106/04/2026

From PhD to Public Company: Jason Kelly on Building Ginkgo and What Comes Next

In this episode of Boba & Biotech, Armon sits down with Jason Kelly, co-founder and CEO of Ginkgo Bioworks, for a conversation about what it takes to build a biotech company from scratch when no one will fund you, why platform business models in biotech are harder than they look, and where he thinks the biggest opportunity in biotech history is hiding.

Details
Light and dark purple banner with the title "Boba & Biotech with Armon Sharei" on top left and a cell cartoon holding a pitchfork on its left hand and pitch fork on the right hand. On the right side of the banner is a black and white picture of the host: Armon Sharei smiling.
SEASON 105/21/2026

The Biotech IPO: What Bankers See That Founders Miss

In this episode of Boba & Biotech, Armon sits down with Mark Dempster, Co-Head of Healthcare Investment Banking at Stifel, to pull back the curtain on what biotech bankers actually do and why it matters more than most founders realize.

Details
Light and dark purple banner with the title "Boba & Biotech with Armon Sharei" on top left and a cell cartoon holding a pitchfork on its left hand and pitch fork on the right hand. On the right side of the banner is a black and white picture of the host: Armon Sharei smiling.
SEASON 105/07/2026

From Bench to Boardroom: What Drug Development Actually Takes

In this episode of Boba & Biotech, Armon sits down with William Pao, a physician-scientist who has run oncology R&D at Roche, served as Chief Development Officer at Pfizer, and is now CEO and Co-Founder of Revelio Therapeutics. Few people have seen drug development from as many angles.

Details
Light and dark purple banner with the title "Boba & Biotech with Armon Sharei" on top left and a cell cartoon holding a pitchfork on its left hand and pitch fork on the right hand. On the right side of the banner is a black and white picture of the host: Armon Sharei smiling.
SEASON 104/23/2026

Learning Biotech, Surviving Near-Death, and Seeing What Others Don’t

In this episode of Boba & Biotech, Sophia Lugo and I grab some delicious boba teas to explore her unconventional path into biotech and the realities of building a company at the frontier of genetic medicine. From her early experiences across Harvard, China, and the Gates Foundation to co-founding Radar during her time at Stanford, Sophia shares how urgency, ambition, and a belief in personal agency shaped her journey. She also discusses Radar’s progress, including its mission to solve targeted mRNA delivery and its next milestone of translating in vitro results into in vivo success.

Details
Light and dark purple banner with the title "Boba & Biotech with Armon Sharei" on top left and a cell cartoon holding a pitchfork on its left hand and pitch fork on the right hand. On the right side of the banner is a black and white picture of the host: Armon Sharei smiling.
SEASON 103/26/2026

What should become a company? Lessons from an academic at the center of biotech translation

What actually makes or breaks a biotech startup - and why is it rarely the science?

Details
Light and dark purple banner with the title "Boba & Biotech with Armon Sharei" on top left and a cell cartoon holding a pitchfork on its left hand and pitch fork on the right hand. On the right side of the banner is a black and white picture of the host: Armon Sharei smiling.
SEASON 103/26/2026

What should become a company? Lessons from an academic at the center of biotech translation

In this episode of Boba & Biotech, I sit down with Klavs Jensen - professor at MIT and former chair of its chemical engineering department - to explore a deceptively simple question: why do some scientific breakthroughs become companies while others never leave the lab?

Details
Light and dark purple banner with the title "Boba & Biotech with Armon Sharei" on top left and a cell cartoon holding a pitchfork on its left hand and pitch fork on the right hand. On the right side of the banner is a black and white picture of the host: Armon Sharei smiling.
SEASON 103/12/2026

From Lab to Company: Engineering the Next Generation of Biotech Founders

In this episode of Boba & Biotech, over matching brown sugar milk teas (great minds, same taste), Souf Aboulhouda, co-founder of Nucleate, and I trace his journey from growing up between France, England, and California to pursuing a PhD in the Church Lab at Harvard - where he first stumbled into the world of biotech startups after watching labmates pitch to investors. 

Details
Light and dark purple banner with the title "Boba & Biotech with Armon Sharei" on top left and a cell cartoon holding a pitchfork on its left hand and pitch fork on the right hand. On the right side of the banner is a black and white picture of the host: Armon Sharei smiling.
SEASON 102/26/2026

Money Meets Molecules: What Biotech Investors Actually Care About

In this episode of Boba & Biotech, I grab a delicious mango-coconut sago with Ileana Pirozzi, a former biotech investor who’s stepping off the venture sidelines and into the founder seat. From growing up in Italy to studying biomedical engineering at Stanford and working at NASA, Ileana shares how venture capital became a crash course in scientific rigor and why it ultimately felt too distant from real impact. The conversation pulls back the curtain on how VC decisions actually get made: why “no” is so hard to say, how fund dynamics and internal politics shape outcomes, and why most firms prefer to follow rather than lead. They dig into what VCs often miss when judging founders, debate generalist versus specialist investors, and call out overrated and underrated trends. The episode closes with a look at what could truly unlock the next wave of clinical impact: rethinking how clinical trials are designed and run.

Details
Light and dark purple banner with the title "Boba & Biotech with Armon Sharei" on top left and a cell cartoon holding a pitchfork on its left hand and pitch fork on the right hand. On the right side of the banner is a black and white picture of the host: Armon Sharei smiling.
SEASON 102/13/2026

Building and Scaling the Tools and Technologies that Underpin Life Sciences

In this episode of Boba & Biotech, I go for a tasty brown sugar milk tea with Martin Madaus, former CEO of one of the biggest technology providers in our field, Millipore, for a wide-ranging conversation on what actually creates value in life sciences.

Details
Light and dark purple banner with the title "Boba & Biotech with Armon Sharei" on top left and a cell cartoon holding a pitchfork on its left hand and pitch fork on the right hand. On the right side of the banner is a black and white picture of the host: Armon Sharei smiling.
SEASON 101/29/2026

Introducing Boba & Biotech: The Only Thing We Sugarcoat is the Boba

In the pilot episode of Boba & Biotech, I try out a homemade milk tea with my long time friend and colleague, Shirley Mao. The goal of this episode is to invite listeners into my world - inside and outside of work - and to share the vision behind this brand-new podcast. It's also the fastest way to figure out if I’m boring or insufferable :)

Details
Light and dark purple banner with the title "Boba & Biotech with Armon Sharei" on top left and a cell cartoon holding a pitchfork on its left hand and pitch fork on the right hand. On the right side of the banner is a black and white picture of the host: Armon Sharei smiling.
SEASON 101/12/2026

Trailer - Welcome to Boba & Biotech, here's the scoop from Armon Sharei

Biotech has a PR problem. It's messy, complex, and hard to understand from the outside looking in. That's why I'm starting Boba & Biotech.

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