Hear how Portal and DKFZ’s DNA Vector Lab are leveraging nanoplasmids and non-integrating episomal vectors to boost gene expression and minimize toxicity in hard-to-transfect cells — bypassing conventional backbone limitations to push...  Read more

DNA-encoded chemical libraries are screened against purified protein outside of cells. Portal changes that — delivering full DEL constructs directly into the cytoplasm of live cells, so selections can run against targets in their native...  Read more

What would you do if you could get anything into any cell? What experiments would you run? What questions would you finally be able to answer? If intracellular delivery is the bottleneck standing between you and a breakthrough, this is...  Read more

Circular RNA is opening new doors for cell engineering from longer-lasting protein expression to multiplexed cargo delivery. Join researchers from MGB's Gene Therapy & Cell Innovation center and Portal Bio for a look at what makes circRNA...  Read more

See how Portal and Promega are enabling AbbVie to test impermeable small molecules, protein degraders, and gene editing constructs directly inside living cells — bypassing traditional permeability limitations to accelerate early drug...  Read more

Learn how Portal's integration with the HighRes PreciseDrop II (PDII) is transforming drug discovery—featuring real-world results from Merck.  Read more